Professor of Diabetes and Autoimmunity

Research Lead, Centre for Diabetes and Metabolic Medicine

 

 

 

Publications since 2001

•  Allen JS, Pang K, Skowera A, Ellis R, Rackham C, Lozanoska-Ochser B, Tree T, Leslie RD, Tremble JM, Dayan CM, Peakman M. Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture. Diabetes. 2009 Jan;58(1):138-45.

•  Thivolet C, Mauricio D, Alemanno I, Cipponeri E, Collier D, Hunter S, Buzzetti R, de Leiva A, Pozzilli P, Leslie RD; Action LADA Group. Metabolic syndrome and autoimmune diabetes: action LADA 3. Hawa MI. Diabetes Care. 2009 Jan;32(1):160-4.

•  Beyan H, Buckley LR, Bustin SA, Yousaf N, Pozzilli P, Leslie RD. Altered monocyte cyclo-oxygenase response in non-obese diabetic mice. Clin Exp Immunol. 2009 Feb;155(2):304-10.

•  Leslie RD, Kilpatrick ES. Translating the A1C assay into estimated average glucose values: response to Nathan et al. Diabetes Care. 2009 Jan;32(1):e11;

•  H.Beyan, R.D.G Leslie. Autoimmune Diseases in Endocrinology (2008)
Type 1 diabetes. Ed. A.P.Weetman.  Humana Press

•  Leslie RD, Kolb H, Schloot NC, Buzzetti R, Mauricio D, De Leiva A, Yderstraede K, Sarti C, Thivolet C, Hadden D, Hunter S, Schernthaner G, Scherbaum W, Williams R, Pozzilli P. Diabetes classification: grey zones, sound and smoke: Action LADA 1. Diabetes Metab Res Rev. 2008 Oct;24(7):511-9.

•  Padmos RC, Schloot NC, Beyan H, Ruwhof C, Staal FJ, de Ridder D, Aanstoot HJ, Lam-Tse WK, de Wit H, de Herder C, Drexhage RC, Menart B, Leslie RD, Drexhage HA; LADA Consortium. Distinct monocyte gene-expression profiles in autoimmune diabetes. Diabetes. 2008 Oct;57(10):2768-73

•  Lawson JM, Tremble J, Dayan C, Beyan H, Leslie RD, Peakman M, Tree TI. Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes. Clin Exp Immunol. 2008 Dec;154(3):353-9

•  Brophy S, Yderstraede K, Mauricio D, Hunter S, Hawa M, Pozzilli P, Schernthaner G, Schloot N, Buzzetti R, Davies H, Leslie D, Williams R; Action LADA Group. Time to insulin initiation cannot be used in defining latent autoimmune diabetes in adults. Diabetes Care. 2008 Mar;31(3):439-41

•  Törn C, Mueller PW, Schlosser M, Bonifacio E, Bingley PJ; Participating Laboratories. Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2. Diabetologia. 2008 May;51(5):846-52.

• Chester A.A., Zaheed H., Charles E.L., Devendra P.D., Stein R., Cay C., Baker A., Beyan H., Hawa M., Ola T., Leslie RDG. Incomplete penetrance of susceptibility genes for MHC-determined immunoglubulin deficiencies in monozygotic twins discordant for type 1 diabetes (2006). J. of  Autoimmunity 2006 Sep; 27(2): 89-95

• Beyan H, Ola T, David R, Leslie G. Ann N Y. Progression of autoimmune diabetes: slowly progressive insulin-dependent diabetes mellitus or latent autoimmune diabetes of adult. Acad Sci. 2006 Oct;1079:81-9.

•  Type 1 diabetes and latent autoimmune diabetes in adults. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2006 dec;31(6):809-13.

•  Beyan H, Goodier MR, Nawroly NS, Hawa MI, Bustin SA, Ogunkolade WB, Londei M, Yousaf N, Leslie RD. Altered monocyte cyclooxygenase response to lipopolysaccharide in type 1 diabetes. Diabetes. 2006 Dec;55(12):3439-45.

•  Alper CA, Husain Z, Larsen CE, Dubey DP, Stein R, Day C, Baker A, Beyan H, Hawa M, Ola TO, Leslie RD. Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes. J Autoimmun. 2006 Sep;27(2):89-95. Epub 2006 Oct 6.

•  Cohen RM, Snieder H, Lindsell CJ, Beyan H, Hawa MI, Blinko S, Edwards R, Spector TD, Leslie RD. Evidence for independent heritability of the glycation gap (glycosylation gap) fraction of HbA1c in nondiabetic twins. Diabetes Care. 2006 Aug;29(8):1739-43.

•  Ola TO, Gigante A, Leslie RD. Latent autoimmune diabetes of adults (LADA). Nutr Metab Cardiovasc Dis. 2006 Apr;16(3):163-7. Epub 2005 Dec 13. Review.

•  Goodier MR, Nawroly N, Beyan H, Hawa M, Leslie RD, Londei M. Identical twins discordant for type 1 diabetes show a different pattern of in vitro CD56+ cell activation. Diabetes Metab Res Rev. 2006 Sep-Oct;22(5):367-75.

•  Leslie RD, Williams R, Pozzilli P. Clinical review: Type 1 diabetes and latent autoimmune diabetes in adults: one end of the rainbow. J Clin Endocrinol Metab. 2006 May;91(5):1654-9. Epub 2006 Feb 14. Review.

•  Hawa MI, Picardi A, Costanza F, D'Avola D, Beretta Anguissola G, Guglielmi C, Mottini G, Fezeu L, Mbanya JC, Leslie RD, Pozzilli P. Frequency of diabetes and thyroid autoantibodies in patients with autoimmune endocrine disease from Cameroon. Clin Immunol. 2006 Feb-Mar;118(2-3):229-32. Epub 2005 Nov 17.

•  Agardh CD, Cilio CM, Lethagen A, Lynch K, Leslie RD, Palmer M, Harris RA, Robertson JA, Lernmark A. Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes. J Diabetes Complications. 2005 Jul-Aug;19(4):238-46.

•  Hawa MI, Bonfanti R, Valeri C, Delli Castelli M, Beyan H, Leslie RD. No evidence for genetically determined alteration in insulin secretion or sensitivity predisposing to type 1 diabetes: a study of identical twins. Diabetes Care. 2005 Jun;28(6):1415-8.

•  Schmidt KD, Valeri C, Leslie RD. Autoantibodies in Type 1 diabetes. Clin Chim Acta. 2005 Apr;354(1-2):35-40. Epub 2005 Jan 13. Review.

•  Leslie RD, Delli Castelli M. Age-dependent influences on the origins of autoimmune diabetes: evidence and implications. Diabetes. 2004 Dec;53(12):3033-40. Review.

•  Leslie RD. Preventing type 1 diabetes mellitus: hype and hope. Clin Med. 2004 Sep-Oct;4(5):442-6.

•  Hawa MI, Valorani MG, Buckley LR, Beales PE, Afeltra A, Cacciapaglia F, Leslie RD, Pozzilli P. Lack of effect of vitamin D administration during pregnancy and early life on diabetes incidence in the non-obese diabetic mouse. Horm Metab Res. 2004 Sep;36(9):620-4.

•  Lohmann T, Londei M, Hawa M, Leslie RD. Humoral and cellular autoimmune responses in stiff person syndrome. Ann N Y Acad Sci. 2003 Sep;998:215-22.

•  Leslie RD, Beyan H, Sawtell P, Boehm BO, Spector TD, Snieder H. Level of an advanced glycated end product is genetically determined: a study of normal twins. Diabetes. 2003 Sep;52(9):2441-4.

•  Delli Castelli M, Leslie RD. Diabetic retinopathy: medical management and assessment. Hosp Med. 2003 Jul;64(7):400-3. Review.

•  Beyan H, Buckley LR, Yousaf N, Londei M, Leslie RD. A role for innate immunity in type 1 diabetes? Diabetes Metab Res Rev. 2003 Mar-Apr;19(2):89-100. Review.

•  Hawa MI, Leslie RD. GAD antigen and its significance in type I diabetes. J Endocrinol Invest. 2002 Jul-Aug;25(7):576. Review. No abstract available.

•  Hawa MI, Beyan H, Buckley LR, Leslie RD. Impact of genetic and non-genetic factors in type 1 diabetes. Am J Med Genet. 2002 May 30;115(1):8-17.

•  Bartsocas CS, Leslie RD. Genetics of diabetes mellitus.
Am J Med Genet. 2002 May 30;115(1):1-3. No abstract available.

•  Leslie RD, Pozzilli P. An introduction to new advances in diabetes. Diabetes Metab Res Rev. 2002 Jan-Feb;18 Suppl 1:S1-6. Review.

•  Snieder H, Sawtell PA, Ross L, Walker J, Spector TD, Leslie RD. HbA(1c) levels are genetically determined even in type 1 diabetes: evidence from healthy and diabetic twins. Diabetes. 2001 Dec;50(12):2858-63.

•  Hawa MI, Leslie RD. Early induction of type 1 diabetes. Clin Exp Immunol. 2001 Nov;126(2):181-3. Review. No abstract available.

•  Metcalfe KA, Hitman GA, Rowe RE, Hawa M, Huang X, Stewart T, Leslie RD. Concordance for type 1 diabetes in identical twins is affected by insulin genotype. Diabetes Care. 2001 May;24(5):838-42.

•  Redondo MJ, Yu L, Hawa M, Mackenzie T, Pyke DA, Eisenbarth GS, Leslie RD. Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia. 2001 Mar;44(3):354-62. Erratum in: Diabetologia 2001 Jul;44(7):927.

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