Home| Non-clinical Lecturer in Epigenetics |
Publications since 2001
• Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Gräf S, Tomazou EM, Bäckdahl L, Johnson N, Herberth M, Howe KL, Jackson DK, Miretti MM, Fiegler H, Marioni JC, Birney E, Hubbard TJ, Carter NP, Tavaré S, Beck S. (2008) An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs ). Genome Res . 18: 1518-29.
• Down TA*, Rakyan VK* (*equal first authors) , Turner DJ, Flicek P, Li H, Kulesha E, Gräf S, Johnson N, Herrero J, Tomazou EM, Thorne NP, Bäckdahl L, Herberth M, Howe KL, Jackson DK, Miretti MM, Marioni JC, Birney E, Hubbard TJ, Durbin R, Tavaré S, Beck S. (2008) A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nat Biotechnol. 26: 779-85.
• Ottaviani D, Lever E, Mitter R, Jones T, Forshew T, Christova R, Tomazou EM, Rakyan VK , Krawetz SA, Platts AE, Segarane B, Beck S, Sheer D. (2008) Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex. Genome Res. 18: 1778-86.
• Novakovic B, Rakyan VK , Ng HK, Manuelpillai U, Dewi C, Wong NC, Morley R, Down T, Beck S, Craig JM, Saffery R. (2008) Specific tumour-associated methylation in normal human term placenta and first-trimester cytotrophoblasts. Mol Hum Reprod. 14: 547-54.
• Tomazou EM, Rakyan VK , Lefebvre G, Andrews R, Ellis P, Jackson DK, Langford C, Francis MD, Bäckdahl L, Miretti M, Coggill P, Ottaviani D, Sheer D, Murrell A, Beck S. (2008) Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis. BMC Med Genomics. 1:19.
• Beck S, Rakyan VK. (2008) The methylome: approaches for global DNA methylation profiling. Trends Genet. 24: 231-7.
• Eckhardt F, Lewin J, Cortese R, Rakyan VK, Attwood J, Burger M, Burton J, Cox TV, Davies R, Down TA, Haefliger C, Horton R, Howe K, Jackson DK, Kunde J, Koenig C, Liddle J, Niblett D, Otto T, Pettett R, Seemann S, Thompson C, West T, Rogers J, Olek A, Berlin K, Beck S. (2006) DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet. 38: 1378-85.
• Rakyan VK, Beck S. (2006) Epigenetic variation and inheritance in mammals. Curr Opin Genet Dev. 16: 573-7.
• Murrell A, Rakyan VK, Beck S. (2005) From genome to epigenome. Hum Mol Genet. 14 Spec No 1:R3-R10.
• Rakyan VK, Hildmann T, Novik KL, Lewin J, Tost J, Cox AV, Andrews TD, Howe KL, Otto T, Olek A, Fischer J, Gut IG, Berlin K, Beck S. (2004) DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project. PLoS Biol. 2: e405.
• Rakyan VK, Chong S, Champ ME, Cuthbert PC, Morgan HD, Luu KV, Whitelaw E. (2003) Transgenerational inheritance of epigenetic states at the murine AxinFu allele occurs after maternal and paternal transmission. Proc Natl Acad Sci U S A. 100: 2538-43.
• Rakyan VK, Whitelaw E. (2003) Transgenerational epigenetic inheritance. Curr Biol. 13: R6.
• Rakyan VK , Blewitt ME, Druker R, Preis JI, Whitelaw E. (2002) Metastable epialleles in mammals. Trends Genet. 18: 348-51.
• Rakyan VK, Preis J, Morgan HD, Whitelaw E. (2001) The marks, mechanisms and memory of epigenetic states in mammals. Biochem J. 356: 1-10.
Book Chapters
• Thorne NP, Marioni JC, Rakyan VK, Ibrahim AEK, Massie C, Curtis C, Brenton JD, Murrell A & Tavaré S. (2008) DNA methylation arrays: Methods and analysis. In Microarray Innovations - Technology and Experimentation, Ed. G. Hardiman. DNA Press.Non-refereed publications
• Morgan H, Preis J, Rakyan VK & Whitelaw E (2001) Inheritance: not only DNA. Today's Life Sciences. 13: 32.
• Rakyan VK (2002) Heredity: not just DNA. SciNews, Faculty of Science, University of Sydney, Australia.
• Rakyan VK (2002) School of Molecular and Microbial Biosciences Research Report, University of Sydney, Australia.
• Rakyan VK (2003, March) A kink in the tail of heredity. Australasian Science.