| Clinical Senior Lecturer |
| Honorary Consultant Surgeon |
Contact details:
| Tel: | +44 20 7377 7000 x3151 |
| Fax: | +44 20 7377 7346 |
| Email: | p.j.lunniss@qmul.ac.uk |
| Address: | Academic Surgical Unit, |
Biography
Following higher surgical training in colorectal surgery at the Royal London Hospital , Mount Sinai Hospital , Toronto , and St. Mark's Hospital, Peter Lunniss was appointed as Senior Lecturer and Honorary Consultant Surgeon in 1997. As a Clinical Academic Colorectal Surgeon, he practices at both Homerton and BLT Hospitals, with clinical emphasis on all aspects of colorectal disease, but with a large tertiary referral practice specifically in complex anal fistula, faecal incontinence and constipation. He is past Chair, NE Thames Network Colorectal Cancer Tumour Board, and is a member of the North Thames Deanery STC.
Research Activity
Research is centred at the Gastrointestinal Physiology Unit, Royal London Hospital, which is the busiest such Unit in the country for the clinical physiological investigation of functional hindgut disorders, principally faecal incontinence and constipation, with the focus on determining underlying pathophysiology within individuals in an attempt to direct targeted, rather than empirical therapies, and to provide the basis for development of novel treatments aimed at correcting the pathophysiologies identified. Over the last five years, emphasis has been on rectal sensorimotor function, and with advances in technology, is progressing into research of colonic motility in health and disease. Research also continues in the development of biomaterials for use in the eradication of chronic anal fistulae whilst preserving the anal sphincters and continence mechanism, which are both threatened by conventional surgery
Key Publications
Lunniss PJ , Armstrong P, Barker PG, Reznek RH and Phillips RKS (1992). Magnetic resonance imaging of anal fistulae. Lancet 340 : 394-396.
Lunniss PJ , Kamm MA and Phillips RKS (1994).Factors affecting continence after surgery for anal fistula. Br J Surg . 81 : 1382-1385.
Lunniss PJ , Skinner S, Britton KE, Granowska M, Morris G and Northover JMA (1999). Radioimmunoscintigraphy in recurrent colorectal cancer. Effect on management and outcome. Br J Surg . 86 : 244-249.
Golder M, Burleigh DE, Belai A, Ghali L, Ashby D, Lunniss PJ , Navsaria HA and Williams NS (2003). Smooth muscle cholinergic denervation hypersensitivity in diverticular disease. Lancet 361 : 1945 - 1951.
Gladman MA, Dvorkin LS, PJ Lunniss , Williams NS and Scott SM (2005). Rectal hyposensitivity: a disorder of the rectal wall, or the afferent pathway? An assessment using the barostat.. Am J Gastroenterol. 100 : 106 -114.
Gladman MG, Scott SM, Lunniss PJ and Williams NS (2005). Systematic review of surgical options for idiopathic megarectum and megacolon. Ann Surg. 241 : 562 - 574.
Dvorkin LS, Gladman MA, Scott SM, Williams NS and PJ Lunniss (2005). Rectal intussusception: a study of rectal biomechanics and visceroperception. Am J Gastroenterol. 100 : 1578 - 1585.
Gladman MG, Williams NS, Scott SM, Ogunbiyi OA and Lunniss PJ (2005). Medium-term results of Vertical Reduction Rectoplasty and sigmoid colectomy for idiopathic megarectum. Br J Surg . 92 : 624 - 630.
Chan CLH, Lunniss PJ , Wang D, Williams NS and Scott SM (2005). Rectal sensorimotor dysfunction in patients with urge faecal incontinence: evidence from prolonged manometric studies. Gut 54 : 1263 - 1272.
Gladman MA, Lunniss PJ , Scott SM and Swash M (2006). Rectal Hyposensitivity . Am J Gastroenterol. 101 : 1140 - 1151.

