Home| Professor of Neurogastroenterology |
| Director, Wingate Institute of Neurogastroenterology |
Publications since 2001
• Hobday D., Aziz Q ., Thacker N., Hollander I. , Thompson DG . A study of the cortical processing of ano-rectal sensation using functional MRI. Brain. 2001;124(Pt2):361-8.
• Aziz Q. Acid Sensors in the gut: a taste of things to come. Euro. J. Gastroenterol Hepatol. 2001;13(8):885-8.
• Hamdy S., Aziz Q., Thompson DG., Rothwell JC. Physiology and pathophysiology of the swallowing area of human motor cortex. Neural Plasticity 2001;8(1-2):91-7.
• Sarkar S., Hobson AR ., Furlong PL. , Woolf CJ., Thompson DG., Aziz Q. Central Neural Mechanisms Mediating Human Visceral Hypersensitivity. American Journal of Physiology: Gastrointestinal and Liver Physiology 2001;281 (5):G1196-202.
• Hobday DI., Hobson AR ., Sarkar S., Furlong PL., Thompson DG ., Q Aziz. The Cortical Processing of Human Gut Sensation: an Evoked Potential Study. American Journal of Physiology. 2002;283 (2):G335-G339.
• Phillips ML., Gregory LJ ., Cullen S., Coen SJ ., Ng V., Andrew C., Giampietro V., Bullmore E., Zelaya F., Amaro E., Thompson DG ., Hobson AR ., Williams SCR., Brammer M., Aziz Q. The Effect of Negative Emotional Context on Neural and Behavioural Responses to Oesophageal Stimulation. Brain 2003;126(Pt 3):669-684.
• Sarkar S., Hobson AR ., Hughes A., Growcott J., Woolf CJ., Thompson DG ., Aziz Q. The Prostanoid EP-1 Receptor Mediates Acid-Induced Visceral Pain hypersensitivity in Man. Gastroenterology 2003;124(1):18-25.
• Harris ML and Aziz Q . Brain-gut interaction in irritable bowel syndrome. Hospital Medicine 2003; 64(5):264-9.
• Hobson AR and Aziz Q . Central Nervous System Processing of Visceral Pain in Health and Disease. News in Physiological Science 2003;18:109-114.
• Okpa K., Morley S., Hobson AR ., Sarkar S., Thompson DG ., Aziz Q . Psychological responses to episodic chest pain. Eur. J. of Pain 2003;7(6):521-529 .
• Gregory LJ., Yaguez L., Williams SCR., Altmann C., Coen SJ., Ng VWK., Brammer MJ., Thompson DG., Aziz Q. Cognitive Modulation of the Cerebral Processing of Human Oesophageal Sensation using Functional Magnetic Resonance Imaging. GUT 2003;52(12):1671-7.
• Biggs AM., Aziz Q., Tomenson B., Creed F. Do Childhood Adversity and Recent Social Stress Predict Health Care Use in Patients Presenting With Upper Abdominal or Chest Pain? Psychosomatic Medicine , 2003;65(6):1020-1028.
• Phillips ML., Gregory LJ., Cullen S., Coen S., Ng V., Andrew C., Giampietro V., Bullmore E., Zelaya F., Amaro E., Thompson DG., Hobson AR., Williams SC., Brammer M., Aziz Q. The effect of negative emotional context on neural and behavioural responses to oesophageal stimulation . Brain 2003 Mar;126(Pt 3):669-84.
• Biggs AM., Aziz Q., Tomenson B., Creed F. The effect of childhood adversity on health-related quality of life in patients with upper abdominal or chest pain. GUT 2004;53(2):180-186.
• Willert RP., Woolf CJ., Hobson AR., Delaney C., Thompson DG., Aziz Q. The Development and Maintenance of Visceral Pain Hypersensitivity is Dependent on the N-Methyl-D-Aspartate Receptor. Gastroenterology 2004;126(3)
• Hobson AR and Aziz Q. Brain Processing of Esophageal Sensation in Health and Disease. Gastroenterology Clinics of North America 2004;33:69-91.
• Furlong PL. , Hobson AR., Aziz Q., Barnes GR. , Singh KD., Hillebrand A. , Thompson DG., Hamdy S. Dissociating the spatio-temporal characteristics of cortical neuronal activity associated with human volitional swallowing in the healthy adult brain. Neuroimage 2004;22(4):1447-55.
• Hobson AR., Khan RW., Sarkar S., Furlong PL and Aziz Q. Development of esophageal hypersensitivity following experimental duodenal acidification. Am J Gastroenterol . 2004;99(5):813-20.
• Matthews PJ., Aziz Q., Facer P., Davis JB., Thompson DG and Anand P. Increased capsaicin receptor TRPV1 nerve fibres in the inflamed human oesophagus. Eur J Gastroenterol Hepatol 2004;16(9):897-902.
• Sarkar S., Thompson DG., Woolf C., Hobson AR., Millane T and Aziz Q. Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression. Am J Gastroenterol. 2004;99(10):1998-2006.
• Van Oudenhove L., Demyttenaere K., Tack J and Aziz Q. Central nervous system involvement in functional gastrointestinal disorders. Best Pract. Res. Clin. Gastroenterol. 2004;18(4):663-80.
• Hobson AR and Aziz Q. Brain Imaging and Functional GI Disorders: has it helped our understanding. GUT 2004;53(8):1198-206.
• Hobson AR., Furlong PL. , Worthen SF., Hillebrand A., Barnes G., Singh K and Aziz Q. Real-time imaging of human cortical activity evoked by painful esophageal stimulation. Gastroenterology 2005; 128(3):610-9.
• Aziz et al. Cortical Processing of Visceral and Somatic Stimulation - Differentiating Pain Intensity from Unpleasantness. Neuroscience 2005 In Press.
• Matthews PJ and Aziz Q. Functional Abdominal Pain. Postgraduate Medical Journal 2005; 81(957):448-85.
• Yág üez L., Coen S., Gregory LJ., Amaro E., Altman C, Williams SCR, Aziz Q. Brain response to visceral aversive conditioning: a Functional Magnetic Resonance Imaging study. Gastroenterology 2005;128(7):1819-29.
• Matthews PJ and Aziz Q. How usefuls are proton-pump inhibitors for diagnosis and therapy of patients with non-cardiac chest pain. Nat Clin Pract Gastroenterol Hepatol 2005;2(11):506-7.
• Geeraerts B., Vandenberghe J., Van Oudenhove L., Gregory LJ., Aziz Q., Dupont P., Demyttenaere K., Janssens J and Tack J. Influence of experimentally induced anxiety on gastric sensorimotor function in man. Gastroenterology 2005 Nov;129(5):1437-44
• Hobson AR., Furlong PL. , Sarkar S., Matthews PJ., Willert RP., Worthen SF., Unsworth BJ and Aziz Q. Neurophysiological assessment of esophageal sensory processing in noncardiac chest pain. Gastroenterology 2006;130(1):80-8.
• Willert RP., Delaney C., Hobson AR., Thompson DG., Woolf CJ and Aziz Q. Constitutive cyclo-oxygenase-2 does not contribute to the development of human visceral pain hypersensitivity. Eur J Pain. 2006 Aug;10(6):487-94.
• Sarkar S., Woolf C., Hobson AR., Thompson DG and Aziz A. Perceptual Wind-Up in the Human Oesophagus is Enhanced by Central Sensitisation. Gut. 2006 Jul; 55(7):920-5.
• Harris ML, Hobson AR, Hamdy S, Thompson DG, Akkermans LM, Aziz Q. Neurophysiological evaluation of healthy human anorectal sensation. Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G950-8.
• Visceral hypersensitivity in Non Erosive Reflux Disease (NERD). Gut . 2007 Dec 13; [Epub ahead of print]
• Paine PA, Hamdy S, Chitnis X, Gregory LJ, Giampietro V, Brammer M, Williams S, Aziz Q. Modulation of Activity in Swallowing Motor Cortex Following Esophageal Acidification: A Functional Magnetic Resonance Imaging Study. Dysphagia . 2007 Oct 23; [Epub ahead of print]
• Dunckley P, Aziz Q, Wise RG, Brooks J, Tracey I, Chang L. Attentional modulation of visceral and somatic pain. Neurogastroenterol Motil . 2007 Jul; 19 ( 7 ): 569-77 .
• Spiller R, Aziz Q, Creed F, Emmanuel A, Houghton L, Hungin P, Jones R, Kumar D, Rubin G, Trudgill N, Whorwell P; Clinical Services Committee of The British Society of Gastroenterology. Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut . 2007 Dec; 56 (12): 1770-98 .
• Coen SJ, Gregory LJ, Yágüez L, Amaro E Jr, Brammer M, Williams SC, Aziz Q. Reproducibility of human brain activity evoked by esophageal stimulation using functional magnetic resonance imaging. Am J Physiol Gastrointest Liver Physiol . 2007 Jul; 293 (1): G188-97 .