Home| Senior Clinical Scientist |
| Manager, GI Physiology Unit |
Contact details:
| Tel: | +44 20 7377 7194 |
| Fax: | +44 20 7377 7346 |
| Email: | m.scott@qmul.ac.uk |
| Address: | Academic Surgical Unit, |
Biography
Mark Scott has a BSc in Physiology & Biology, and in 1998 was awarded a PhD in Physiology / Medicine from the University of London for his work on "Prolonged monitoring of colonic motor activity by an ambulatory recording technique". He has considerable experience, both clinical and academic, related to the physiological investigation of functional gastrointestinal disorders, and was integral to setting up the GI Physiology Unit at the Royal London Hospital , which he has managed on a day-to-day basis for the past 9 years. The Unit has an international reputation, and provides a clinical service to >2500 patients per year, which supplies the resources for aligned research; there are currently ~20 full-time and affiliated staff members.
Research Activity
Mark's principal interest is neurogastroenterology and motility, and applied physiology; together with Professor Qasim Aziz, he has been one of the founding members of the Neurogastroenterology Group at QMUL, which comprises 34 academic staff from Surgery, Gastroenterology, Neuroscience and Pathology. He is the author of over 60 peer-reviewed publications, and 7 book chapters, and together with Mr Peter Lunniss and Mr Charles Knowles (under the directorship of Professor Norman Williams) leads a flourishing research programme centered on clinical GI (principally colorectal) physiological investigation, involving the supervision of several research fellows. This groups' pioneering work on visceral hyposensitivity is rapidly gaining international recognition. Other clinical research interests include:
• gastrointestinal motility and the physiological investigation of gastrointestinal sensorimotor function, both in health and disease;
• assessment and development of novel equipment / techniques for gastrointestinal function testing;
• on the basis of detailed assessment (symptoms, clinical, physiological), to determine the effects of conventional and novel surgical procedures, and other therapeutic measures.
Key Publications
• Scott SM , Picon L, Knowles CH, Fourquet F, Yazaki E, Williams NS, Lunniss PJ, Wingate DL. Automated quantitative analysis of nocturnal jejunal motor activity identifies abnormalities in individuals and subgroups of patients with slow-transit constipation. Am J Gastroenterol 2003; 98 : 1123-34
• Scott SM . Manometric techniques for the evaluation of colonic motor activity: current status. Neurogastroenterol Motil 2003; 15 : 483-513
• Chan CLH, Lunniss PJ, Wang D, Williams NS, Scott SM . Rectal sensorimotor dysfunction in patients with urge faecal incontinence: evidence from prolonged manometric studies. Gut 2005; 54 : 1263-72
• Gladman MA, Lunniss PJ, Scott SM , Swash M. Rectal hyposensitivity Am J Gastroenterol 2006; 101 : 1140-51
• Zarate N, Knowles CH, Newell M, Garvie NW, Gladman MA, Lunniss PJ, Scott SM . In patients with slow transit constipation, the pattern of colonic transit delay does not differentiate between those with or without impaired rectal evacuation Am J Gastroenterol 2007; in press
