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Dr Daniel J. Pennington Phd
Reader in Molecular Immunology

 

 

Publications since 2001

•  Ribot J. C., deBarros A., Pang D. J., Neves J. F., Peperzak V., Roberts S. J. Girardi M., Borst J. Hayday A. C., Pennington D. J., Silva-Santos B. (2009). CD27 is a thymic determinant of the balance between interferon-g- and interleukin-17-producing gd T cell subsets. Nat Immunol. 10(4) p427-436.

•  Hayday A. C. and Pennington D. J. (2007). Key factors in the organised chaos of early T cell development Nat Immunol 8(2) p137-144.

•  Pennington D. J., Silva-Santos B., Silberzahn T., Escorcio-Correia M., Woodward M. J., Roberts S. J., Smith A. L., Dyson P. J., and Hayday A. C. (2006). Early events in the thymus affect the balance of effector and regulatory T cells. Nature 444 (7122) p1073-1077.

•  Pennington D. J.*, Silva-Santos B.* and Hayday A. C. (2005). Lymphotoxin-Mediated Regulation of gd Cell Differentiation by ab T Cell Progenitors. Science 307 p925-928. Published online 9 th December 2004; 10.1126/science.1103978. (A "perspective" by E. Rothenberg accompanied this article). ( * Joint authors)

•  Pennington D. J., Vermijlen D., Wise E. L., Clarke S. L., Tigelaar R. E. and Hayday A. C. (2005). The integration of conventional and unconventional T cells that characterizes cell-mediated responses. Adv Immunol 87 p27-59.

•  Pennington D. J. , Silva-Santos B. and Hayday A. C. (2005). gd T cell development - having the strength to get there. Curr Opin Immunol 17(2) p108-115.

•  Pennington D. J. *, Silva-Santos B.*, Shires J., Theodoridis E., Pollitt C., Wise E. L., Tigelaar R. E., Owen M. J. and Hayday A. C. (2003). The inter-relatedness and interdependence of mouse T cell receptor gd + and ab + cells. Nat Immunol 4(10) p991-998. ( * Joint authors)

•  Pennington D. J. , Giuggio V. M., and Hayday A. C. (2003). Editorial: Genomics and immunology. Sem Immunol 15 p201-208.

•  Trigueros C., Hozumi K., Silva-Santos B., Bruno L., Hayday A. C., Owen M. J. and Pennington D. J. (2003). Pre-TCR signalling regulates IL-7 receptor a expression promoting thymocyte survival at the transition from the double-negative to double-positive stage. Eur J Immunol 33 p1968-1977.

•  Comalada M., Xaus J., Valledor A. F., López-López C., Pennington D. J. and Celada A. (2003). PKC e is involved in JNK activation that mediates LPS-induced TNF- a which induces apoptosis in macrophages. Am J Physiol Cell Physiol 285(5) C1235-45 .

•  Aliberti J., Schulz O., Pennington D. J. , Tsujimura H., Reis e Sousa C., Ozato K. & Sher A. (2003) Essential role for ICSBP in the development of murine CD8 a + dendritic cells. Blood 101 p305-310.

•  Saurin, A. T., Pennington, D. J. , Raat, N. J., Latchman D. S., Owen, M. J. and Marber, M. S. (2002). Targetted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts. Cardiovasc Res 55 p672-680.

•  Leask A., Abraham D. J., Finlay D. R., Holmes A., Pennington D. J. , Shi-Wen X., Chen Y., Venstrom K., Dou X., Ponticos M., Black C., Bernabeu C., Jackman J. K., Findell P.R., Connolly M.K. (2002). Dysregulation of transforming growth factor beta signaling in scleroderma: overexpression of endoglin in cutaneous scleroderma fibroblasts. Arthritis Rheum 46(7) p1857-1865.

•  Schulz, O., Pennington , D. J. , Hodivala-Dilke, K., Febbraio M., and Reis e Sousa, C. (2002) CD36 or a v b 3 and a v b 5 integrins are not essential for MHC class I cross-presentation of cell-associated antigen by CD8 a + murine dendritic cells. J Immunol 168 p6057-6065.

•  Pennington, D. J. *, Castrillo, A.*, Otto, F., Parker P.J., Owen M.J. and Bosca, L. (2001). Protein kinase C epsilon is required for macrophage activation and defence against bacterial infection. J Exp Med 194(9) p1231-1242. ( * Joint authors)

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