Home| Non-Clinical Senior Lecturer in Immunology |
Publications since 2001
• A.J. Stagg , K.E. Norin, T. Midtvedt, M.A. Kamm, S.C. Knight & B. Björkstén Mesenteric dendritic cells from germ-free mice cause less T -cell stimulation but still induce a 4 b 7 integrin. Microbial Ecology in Health and Disease (In Press 2007)
• N. E. McCarthy, H. A. Jones, N. A. Marks, R. J. Shiner, P. W. Ind, H. O. Al-Hassi, N. R. English, C. M. Murray, J. Lambert, S. C. Knight and A. J. Stagg Inhaled allergen driven CD1 up-regulation and enhanced antigen uptake by activated human respiratory-tract dendritic cells in atopic asthma. Clinical and Experimental Allergy 37 72-82 (2007).
• J.O. Lindsay, K. Whelan , A.J. Stagg , P. Gobin, h. Omar Al-Hassi, N. Rayment, M. Kamm, S.C Knight and A. Forbes The clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease. Gut 55 348-355 (2006)
• R.J. Critchley-Thorne, A.J. Stagg and G. Vassaux Recombinant E. Coli expressing invasion targets the Peyer's patches: the basis for a bacterial formulation for oral vaccination. Molecular Therapy 14 183-191 (2006)
• A. L. Hart, H. Omar Al-Hassi, R. Rigby, S. J. Bell, A. V. Emmanuel, S. C. Knight, M. A. Kamm and A. J. Stagg Characteristics of intestinal dendritic cells in inflammatory bowel diseases. Gastroenterology (2005) 129 50-65
• R.J. Rigby, S.C. Knight, M.A. Kamm and A.J. Stagg Differential production of IL-10 and IL-12 by murine colonic dendritic cells in response to microbial stimuli Clin. Exp. Immunol (2005) 139 245-256
• M.R. Mason, A.J. Stagg , S.C.Knight and R.F. Lamont Dendritic cells in umbilical cord blood: a novel technique using small volumes of whole blood. J. Soc. Gynecol. Investig. (2005) 12 246-252
• A. L. Hart, K. Lammers, P. Brigidi, B. Vitali, F. Rizzello, P. Gionchetti, M. Campieri, M. A. Kamm, S. C. Knight and A. J. Stagg Modulation of human dendritic cell phenotype and function by probiotic bacteria. Gut (2004) 53 1602-1609
• A.L.Hart, M.A.Kamm, S.C.Knight and A.J.Stagg . Prospective evaluation of intestinal homing memory T cells in ulcerative colitis . Inflam. Bowel Dis. (2004) 10 496-503
• F. Burke, A.J. Stagg , P.A. Bedford, N. English and S.C. Knight IL-10 producing B220+ CD11c- antigen presenting cells in mouse spleen (2004) J. Immunol. (2004) 173 2362-2372
• A.L. Hart, M.A. Kamm, S.C. Knight and A.J. Stagg Quantitative and functional characterisation of intestinal homing memory T cells: analysis of Crohns disease patients and healthy controls. Clin Exp. Immunol. (2004) 135 137-145
• A.J. Stagg , A.L. Hart, M.A. Kamm and S.C. Knight The dendritic cell: its role in intestinal inflammation and relationship with gut bacteria. Gut (2003) 52 1552-1559
• A.J. Stagg , M.A. Kamm and S.C. Knight Intestinal dendritic cells increase T cell expression of a 4 b 7 integrin. Eur J. Immunol. (2002) 32 1445-1454
• H. Jebbari, A.J. Stagg , R.N. Davidson and S.C. Knight Leishmania major promastigotes inhibit dendritic cell motility in vitro. Infect Immun. (2002) 70 1023-1026
• S.J. Bell, R. Rigby, N. English, S.D. Mann, S.C. Knight, M.A. Kamm and A. J. Stagg Migration and maturation of human colonic dendritic cells. J. Immunol (2001) 166 4958-4967
• P. Konecny, A.J. Stagg , H. Jebbari, N. English, R.N. Davidson and S.C. Knight Murine dendritic cells internalize Leishmania major promastigotes, produce IL-12p40 and stimulate primary T cell proliferation in vitro . Eur. J. Immunol (2001) 29 1803-1811
A.J. Stagg , E. Wunderink, M. Tuffrey, C. Woods and S.C. Knight Protection against ascending infection of the genital tract by Chlamydia trachomatis is associated with rapid recruitment of MHC class II + antigen presenting cells (APC) into uterine tissue. Infection and Immunity (1998) 66 3535-3544
Books
• A. L. Hart, A.J. Stagg , H. Graffner, H. Glise, P. Falk and M.A. Kamm (Eds) Gut Ecology (Martin Dunitz, London 2002)
• S. Robinson and A.J. Stagg (Eds) Methods in Molecular Medicine: Dendritic Cells. (Human Press, Totawa , NJ , 2001)
Invited Reviews and Reports
• S.C. Knight, P.A. Bedford and A.J. Stagg Mixed Leukocyte Reactions. (In: Measuring Immunity. Eds: M.L. Lotze and A.W. Thomson p351-360. Elsevier, London , 2005)
• A.J. Stagg , A.L. Hart, S.C. Knight and M.A. Kamm Interactions between dendritic cells and bacteria in the regulation of intestinal immunity Best Practice and Research Clinical Gastroenterology (2004) 18 255-270
• A.L.Hart, A.J. Stagg and M.A. Kamm Use of probiotics in treatment of inflammatory bowel disease. (2003) J.Clin. Gastroenterol. 36 111-119
• A.L. Hart, A.J.Stagg . M. Frame. H. Graffner, H. Glise and P. Falk The role of gut flora in health and disease and its modification in therapy. Aliment. Pharmacol. Ther. (2002) 16 1838-1393
• A.J. Stagg. Modification of host cell function by normal flora a molecular perspective (In Gut Ecology. Eds: A.L. Hart, A.J. Stagg, H.Graffner, H. Glise, P.Falk and M.A. Kamm. P51-56. Martin Dunitz, London , 2002)
• A.J. Stagg and S.C. Knight . Antigen-presenting cells. In: Encyclopaedia of Life Sciences (2001); Nature Publishing Group 2001
• A.J. Stagg , F. Burke, S .Hill and S.C. Knight Isolation of mouse spleen dendritic cells (In Dendritic Cell Protocols. Eds S.P. Robinson and A.J. Stagg, Humana Press, Totowa NJ 2001)