Clinical Senior Lecturer

Honorary Consultant

 

 

 

Contact details:

Tel:	+44 20 7882 2317
Fax:	+44 20 7882 2181
Email:	d.w.wareham@qmul.ac.uk
Address:	Centre for Immunology and Infectious Disease, Barts and The London School of Medicine and Dentistry, 4 Newark Street, London E1 2AT, United Kingdom

 

 

 

 

 

 

 

Biography

David Wareham qualified from the London Hospital Medical College in 1994 and trained in general medicine in East London and Essex before specialist training in Medical Microbiology in North East Thames. He was awarded a Clinical Training Fellowship to study aspects of Pseudomonas aeruginosa pathogenicity at Queen Mary University in 2002, and was appointed as Senior Clinical Lecturer in Microbiology in July 2005. He is an Honorary Consultant Microbiologist at Barts and The London and Newham University NHS Trusts where he is responsible for aspects of intensive care microbiology.

 

Research Activity

Non-fermentative bacteria such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia are an important cause of nosocomial infection in the immunosuppressed and critically ill yet are increasingly difficult to treat due to multi-drug resistance. I am interested in the characterisation of putative virulence determinants from clinical isolates using both in-vitro models and the human serum antibody response to infection. A fuller understanding of how these organisms colonise and invade susceptible individuals and persist in the hospital environment will help design novel treatment and control strategies for these emerging pathogens.

 

See also: Stenotrophomonas maltophilia Quinolone Protection Proteins (SmQnr)

 

Key Publications

•  Edwards J, Patel G, Wareham DW. Action of Commercial Alcohol Handrubs on the Growth and Secretion of Extracellular Proteins from Multidrug Resistant Strains of Acinetobacter baumannii , Journal of Medical Microbiology 2007, 56: 1595 - 1599

•  Wareham DW, Curtis MA . A Genotypic and Phenotypic Comparison of Type III Secretion Profiles of Pseudomonas aeruginsoa Cystic Fibrosis and Bacteremia Isolates, International Journal of Medical Microbiology , 2007, 297: 227- 234

•  Pumbwe L, Wareham DW, Aduse-Opoku, J, Brazier JS, Wexler HM. Genetic analysis of mechanisms of multidrug resistance in a clinical isolate of Bacteroides fragilis. Clinical Microbiology and Infection 2007,13:183 - 189

•  Wareham DW, Wilks M, Ahmed D, Brazier JS, Millar M. Anaerobic sepsis due to multresistant Bacteroides fragilis: microbiological cure and clinical response with linezolid therapy. Clinical Infectious Disease 2005, 40:e67-e68

>> Publications since 2001

 

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