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Dr Klaus Schmierer PhD, CCT (Neurology)
Clinical Senior Lecturer in Neuroimmunology & Consultant Neurologist (Hon)

 

 

Publications since 2001

• Schmierer K, Parkes HG, So PW, An SF, Brandner S, Ordidge RJ, Yousry TA, Miller DH. High field (9.4 Tesla) magnetic resonance imaging of cortical grey matter lesions in multiple sclerosis. Brain. 2010 Mar;133(Pt 3):858-67.

• Farrell RA, Antony D, Wall GR, Clark DA, Fisniku L, Swanton J, Khaleeli Z, Schmierer K, Miller DH, Giovannoni G. Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI. Neurology. 2009 Jul 7;73(1):32-8.

• Fisniku LK, Altmann DR, Cercignani M, Tozer DJ, Chard DT, Jackson JS, Miszkiel KA, Schmierer K, Thompson AJ, Miller DH. Magnetization transfer ratio abnormalities reflect clinically relevant grey matter damage in multiple sclerosis. Mult Scler. 2009 Jun;15(6):668-77.

• Goodman AD, Rossman H, Bar-Or A, Miller A, Miller DH, Schmierer K, Lublin F, Khan O, Bormann NM, Yang M, Panzara MA, Sandrock AW; GLANCE Investigators. GLANCE: results of a phase 2, randomized, double-blind, placebo-controlled study. Neurology. 2009 Mar 3;72(9):806-12.

•.Schmierer K, Parkes HG, So PW. Direct visualization of remyelination in multiple sclerosis using T2-weighted high-field MRI. Neurology. 2009 Feb 3;72(5):472.

• Kappos L, Gold R, Miller DH, Macmanus DG, Havrdova E, Limmroth V, Polman CH, Schmierer K, Yousry TA, Yang M, Eraksoy M, Meluzinova E, Rektor I, Dawson KT, Sandrock AW, O'Neill GN; BG-12 Phase IIb Study Investigators. Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet. 2008 Oct 25;372(9648):1463-72. Erratum in: Lancet. 2009 Apr 18;373(9672):1340.

• Petzold A, Gveric D, Groves M, Schmierer K, Grant D, Chapman M, Keir G, Cuzner L, Thompson EJ. Phosphorylation and compactness of neurofilaments in multiple sclerosis: indicators of axonal pathology. Exp Neurol. 2008 Oct;213(2):326-35.

• Schmierer K, Wheeler-Kingshott CA, Tozer DJ, Boulby PA, Parkes HG, Yousry TA, Scaravilli F, Barker GJ, Tofts PS, Miller DH. Quantitative magnetic resonance of postmortem multiple sclerosis brain before and after fixation. Magn Reson Med. 2008 Feb;59(2):268-77.

•.Tofts PS, Jackson JS, Tozer DJ, Cercignani M, Keir G, MacManus DG, Ridgway GR, Ridha BH, Schmierer K, Siddique D, Thornton JS, Wroe SJ, Fox NC. Imaging cadavers: cold FLAIR and noninvasive brain thermometry using CSF diffusion. Magn Reson Med. 2008 Jan;59(1):190-5.

• .Schmierer K, Tozer DJ, Scaravilli F, Altmann DR, Barker GJ, Tofts PS, Miller DH. Quantitative magnetization transfer imaging in postmortem multiple sclerosis brain. J Magn Reson Imaging. 2007 Jul;26(1):41-51.

• Schmierer K, Wheeler-Kingshott CA, Boulby PA, Scaravilli F, Altmann DR, Barker GJ, Tofts PS, Miller DH. Diffusion tensor imaging of post mortem multiple sclerosis brain. Neuroimage. 2007 Apr 1;35(2):467-77. Epub 2006 Dec 16.

• Cercignani M, Symms MR, Schmierer K, Boulby PA, Tozer DJ, Ron M, Tofts PS, Barker GJ. Three-dimensional quantitative magnetisation transfer imaging of the human brain.Neuroimage. 2005 Aug 15;27(2):436-41.

• Schmierer K, Scaravilli F, Altmann DR, Barker GJ, Miller DH. Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann Neurol. 2004 Sep;56(3):407-15.

• Symms M, Jäger HR, Schmierer K, Yousry TA. A review of structural magnetic resonance neuroimaging. J Neurol Neurosurg Psychiatry. 2004 Sep;75(9):1235-44. Review.

• Schmierer K, Altmann DR, Kassim N, Kitzler H, Kerskens CM, Doege CA, Aktas O, Lünemann JD, Miller DH, Zipp F, Villringer A. Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study. Mult Scler. 2004 Apr;10(2):182-7.

• Mottershead JP, Schmierer K, Clemence M, Thornton JS, Scaravilli F, Barker GJ, Tofts PS, Newcombe J, Cuzner ML, Ordidge RJ, McDonald WI, Miller DH. High field MRI correlates of myelin content and axonal density in multiple sclerosis--a post-mortem study of the spinal cord. J Neurol. 2003 Nov;250(11):1293-301.

• Schmierer K, Scaravilli F, Barker GJ, Gordon R, MacManus DG, Miller DH. Stereotactic co-registration of magnetic resonance imaging and histopathology in post-mortem multiple sclerosis brain. Neuropathol Appl Neurobiol. 2003 Dec;29(6):596-601.

• Grosse P, Schulz J, Schmierer K. Diagnostic pitfalls in eosinophilic cryptococcal meningoencephalitis. Lancet Neurol. 2003 Aug;2(8):512.

• Schreiber SJ, Doepp F, Bender A, Schmierer K, Valdueza JM. Diffuse cerebral angiomatosis. Neurology. 2003 Apr 8;60(7):1216-8.
19.

•  Dobson-Stone C, Danek A, Rampoldi L, Hardie RJ, Chalmers RM, Wood NW, Bohlega S, Dotti MT, Federico A, Shizuka M, Tanaka M, Watanabe M, Ikeda Y, Brin M, Goldfarb LG, Karp BI, Mohiddin S, Fananapazir L, Storch A, Fryer AE, Maddison P, Sibon I, Trevisol-Bittencourt PC, Singer C, Caballero IR, Aasly JO, Schmierer K, Dengler R, Hiersemenzel LP, Zeviani M, Meiner V, Lossos A, Johnson S, Mercado FC, Sorrentino G, Dupré N, Rouleau GA, Volkmann J, Arpa J, Lees A, Geraud G, Chouinard S, Németh A, Monaco AP. Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis. Eur J Hum Genet. 2002 Nov;10(11):773-81.

• Schmierer K, Irlbacher K, Grosse P, Röricht S, Meyer BU. Correlates of disability in multiple sclerosis detected by transcranial magnetic stimulation. Neurology. 2002 Oct 22;59(8):1218-24.

• Schmierer K. [Medical history and politics: careers of Fritz Lejeune during the Weimar Republic and national socialism] Abh Gesch Med Naturwiss. 2002;(96):1-292. German.

• Schmierer K, Grosse P, De Camilli P, Solimena M, Floyd S, Zschenderlein R. Paraneoplastic stiff-person syndrome: no tumor progression over 5 years. Neurology. 2002 Jan 8;58(1):148.

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