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Professor Jonathan Grigg BSc, MB.BS. MD, MRCP, FRCPCH.
Professor of Paediatric Respiratory and Environmental Medicine

 

 

Publications since 2001

  1. McNally T, Grigg J. Parental understanding of a randomised double-blind controlled trial involving preschool children with viral wheeze. Paediatric Nursing 2001;13:11-14.
  2. Bunn HJ, Dinsdale D, Smith T, Grigg J. Ultrafine particles in alveolar macrophages from normal children. Thorax 2001:56:932-934.
  3. Bunn HJ, Hewitt CRA, Grigg J. Suppression of autologous peripheral blood mononuclear cell proliferation by alveolar macrophages from young infants. Clinical and Experimental Immunology 2002;128:313-317.
  4. Grigg J. The health effects of fossil fuel derived particles. Archives of Disease in Childhood 2002;86:79-83.
  5. Grigg J, Donaldson K, MacNee W, McGarr C, Hewitt CRA. Homotypic aggregation of alveolar macrophages induced by ultrafine carbon black is associated with upregulation of intercellular adhesion molecule-1. Annals of Occupational Hygiene 2002;46S:227-230
  6. Bunn HJ, Woltmann G, Grigg J. Applicability of laser scanning cytometry to the study of paediatric alveolar macrophages. European Respiratory Journal. 2002;20:1437-1443.
  7. Birring SS, Brightling CE, Pradding P, Entwisle JJ, Vara DD, Grigg J, Wardlaw AJ, Pavord ID. Clinical, radiological and induced sputum features of chronic obstructive pulmonary disease in non-smokers. A descriptive study. American Journal of Respiratory and Critical Care Medicine. 2002;166:1078-1083.
  8. Oommen A, Grigg J. Urinary leukotriene E4 in preschool children with acute clinical viral-wheeze. European Respiratory Journal. 2003;21:149-154.
  9. Oommen A, Patel R, Browning M, Grigg J. Systemic neutrophil activation in acute preschool viral-wheeze. Archives of Disease in Childhood. 2003;88:529-531.
  10. Oommen A, McNally T, Grigg J. Eosinophil activation in preschool viral-wheeze. Thorax. 2003;58:876-879.
  11. Oommen A, Lambert PC, Grigg J. Efficacy of a short course of oral prednisolone for viral-wheeze in children aged 1-5 years: randomised controlled trial. Lancet. 2003;362:1433-1438.
  12. Grigg J. Environmental toxins; their impact on children's health. Archives of Disease in Childhood. 2004;89:244-250
  13. Bunn HJ, Kobzik L, Grigg J. MARCO expression on pediatric alveolar macrophages. Cytometry. 2004:60B:45-56
  14. Grigg J. Treatment of paediatric asthma - best practice. Postgraduate Medical Journal. 2004;80:535-540.
  15. Grigg J. Good Research Conduct.  Archives of Disease in Childhood. 2005;90:226-235
  16. McNally T, Peck K, Grigg J. Hospital readmissions for preschool viral-wheeze. Paediatric Nursing.  2005 Oct;17(8):15-8.
  17. Kulkarni NS, Prudon B, Panditi SL, Abebe Y, Grigg J. Carbon loading of alveolar macrophages in adults and children exposed to biomass smoke particles. Science of the Total Environment. 2005;345:23-30
  18. Grigg J. Gaseous air pollution: a danger to infants? Archives of Disease in Childhood. 2005;90:661-664
  19. McNally T, Peck K, Grigg J. Hospital readmissions for preschool viral-wheeze. Paediatric Nursing. 2005;17:1-4.
  20. Mudway IS, Duggan ST,Venkataraman, Kelly FJ, Grigg J. Combustion of the biomass fuel dung cake results in the generation of highly redox active fine particulates. Particle and Fibre Toxicology. 2005;2:6 (1-11)
  21. Panickar J, Kenia P, Silverman M, Grigg J. Intramuscular triamcinolone for difficult asthma. Pediatric Pulmonology 2005;31:421-5.
  22. Pierse N, Rushton L, Harris R, Kuehni CE, Silverman M, Grigg J. Locally-generated particulate pollution and respiratory symptoms in young children. Thorax. 2006. 61:216-20.
  23. Expert Panel on Air Quality Standards Halogens and Hydrogen Halide. Department for Environment, Food and Rural Affairs 2006 Defra Publications, London 1-77.
  24. Michel G, Silverman M, Strippoli MF, Zwahlen M, Brooke A, Grigg J, Kuehni CE Parental understanding of 'wheeze' and its impact on asthma prevalence estimates. European Respiratory Journal 2006;28 1124-1130
  25. Kulkarni N, Pierse N, Rushton L, Grigg J. Carbon in airway macrophages and lung function in children. New England Journal of Medicine.2006 Jul 6;355:21-30
  26. Rao S, Grigg J. New insights into pulmonary inflammation in cystic fibrosis. Archives of Disease in Childhood 2006;786-788.
  27. Panickar J, Grigg J. Controversies in the treatment of preschool wheeze. Paediatric Respiratory Reviews 2006 7:293-8.
  28. Grigg J, Silverman M. Wheezing disorders in young children: one disease or several phenotypes? European Respiratory Monograph 2006;11:153-169.
  29. Grigg J (primary author). Preschool viral wheeze in primary care. Drugs and Therapeutic Bulletin 2007 45: 17-20.
  30. Panickar J, Bhatnagar N, Grigg J Exhaled nitric oxide after a single dose of intramuscular triamcinolone in children with difficult to control asthma. Pediatric Pulmonology 2007;42:573-578.
  31. Grigg J, Cooke MS, Panickar J. Case 3- A boy with respiratory insufficiency New England Journal of Medicine 2007;356:2329-2330.
  32. Kulkarni N, Cooke MS, Grigg J. Neutrophils in induced sputum from healthy children: role of interleukin-8 and oxidative stress. Respiratory Medicine 2007;101:2108-12.
  33. Grigg J. Effect of biomass smoke on pulmonary host defense mechanisms. Paediatric Respiratory Reviews 2007;8:287-291.
  34. Grigg J, Kulkarni N, Pierse N, Rushton L, O’Callaghan C, Rutman A. Black pigmented material in airway macrophages from normal children: association with lung function and modelled locally derived PM10. Health Effects Institute Research Report 2008
  35. Kulkarni N, Grigg J. Air pollution and children’s health. Paediatrics and Child Health 2008;18:238-243
  36. Grigg J. Year in Review; Asthma. Paediatric Respiratory Reviews 2008;9:134-138
  37. Brand PL, Baraldi E, Bisgaard H, Boner AL, Castro-Rodriguez JA, Custovic A, de Blic J, de Jongste JC, Eber E, Everard ML, Frey U, Gappa M, Garcia-Marcos L, Grigg J, Lenney W, Le Souëf P, McKenzie S, Merkus PJ, Midulla F, Paton JY, Piacentini G, Pohunek P, Rossi GA, Seddon P, Silverman M, Sly PD, Stick S, Valiulis A, van Aalderen WM, Wildhaber JH, Wennergren G, Wilson N, Zivkovic Z, Bush A. Definition, assessment and treatment of wheezing disorders in preschool children – an evidence based approach; European Respiratory Society Task Force Report European Respiratory Journal 2008; 32:1096-1110
  38. Rao S, Wright AK, Montiero W, Ziegler-Heitbrock L, Grigg J. Monocyte chemoattractant chemokines in cystic fibrosis. Journal of Cystic Fibrosis 2009 ;8(2):97-103
  39. Panickar J, Lakhanpaul M, Lambert PC, Kenia P, Stephenson T, Smyth A, Grigg J. A Randomized, Controlled Trial of Oral Prednisolone for Preschool Children Hospitalized with Acute Viral-Wheeze New England Journal of Medicine 2009;360;329-338
  40. Wright AK, Rao S, Range S, Eder C, Hofer T, Frankenberger M, Kobzik L, Brightling C, Grigg J,  Ziegler-Heitbrock L. Expansion of Small Sputum Macrophages in Cystic Fibrosis: Failure to express MARCO and Mannose-Receptors. Journal of Leukocyte Biology April 2009 epub ahead of print
  41. Grigg J. New insights into preschool wheeze (editorial). Clinical and Experimental Allergy 2009;39:179-80.
  42. Fullerton DG,  Jere K, Jambo K,  Kulkarni NS, Zijlstra EE, Grigg J, French N, Molyneux ME, Gordon SB.  Domestic smoke exposure is associated with alveolar macrophage particulate load Tropical Medicine and International Health 2009;14;349-354.
  43. Expert Panel on Air Quality Standards Metals and Metalloids. Guidelines for metals and metalloids in ambient air for the protection of human health. Department for Environment, Food and Rural Affairs Publications, London 2009.
  44. Expert Panel on Air Quality Standards Metals and Metalloids. Addendum to guidelines for metals and metalloids in ambient air for the protection of human health. Department for Environment, Food and Rural Affairs Publications, London 2009.
  45. Lenney W, Boner AL, Bont L , Bush A, Carlsen KH, Eber E, Fauroux B, Götz M,  Greenough A, Grigg J, Hull J, Kimpen J, Sánchez Luna M, de Benedictis FM. Medicines used in respiratory disease only seen in children European Respiratory Journal 2009 in press.
  46. Grigg J The role of steroids in acute preschool wheeze Archives of Disease in Childhood (leading article). in press.
  47. Grigg J The wheezy preschool child. Paediatrics and Child Health. in press.
  48. Grigg J Management and treatment of preschool wheeze. General Practice Update. in press.
  49. Grigg J Particulate Air Pollution and Vulnerability to Respiratory Infections in Children. In; Allergens, Pollutants, and Innate Immunity Ed. Williams M in press.
  50. Grigg J. Biomass smoke and infection: mechanisms In; Encyclopedia of Environmental Health, Ed. Nriagu J. Elesvier BV. in press.
  51. Grigg J Particulate matter exposure in children; relevance to COPD.  Proceedings of the American Thoracic Society. in press.
  52. Grigg J, Tellabati A, Rhead S, Almeida GM, Higgins JA, Bowman KJ, Jones GDD, Howes P. DNA damage of macrophages at an air-tissue interface induced by metal nanoparticles. Nanotoxicology.  in press

 

Other publications


  1. Grigg J. The lung after injury in children. In: Injury in the young. Eds Little& Ward-Platt. Cambridge University Press.1998
  2. Bunn HJ, Grigg J. Air pollution and respiratory disease in children: evidence for an association. Asthma Journal 2000;5:168-172.
  3. Grigg J, Browning M, Silverman M. Inflammation and Respiratory Disease. In; Practical Respiratory Paediatrics. eds. Silverman & O’Callaghan. Arnold 2001; 82-104.
  4. Grigg J. Inflammation. In; Childhood Asthma and other Wheezing Disorders. Ed Silverman M. Arnold 2002;173-182.
  5. Grigg J, Silverman M, McKean M. Virus Induced Wheeze in Young Children - A Separate Disease? In; Respiratory Infections in Allergy and Asthma. Ed  Johnston SL, Papadopoulos NG. Marcel Dekker, Inc New York 2003;427-471.
  6. Grigg J. Prenatal inflammation of lungs and bronchopulmonary dysplasia.  Pediatrics 1997;99:144
  7. Grigg J. Particulate puzzles pondered. Lancet 1999:354:1451.
  8. Grigg J. Oral steroids and inflammatory markers in asthma. Archives of  Disease in Childhood 2001;84:187
  9. Grigg J. Wheezing disorders in the preschool child. Thorax 2004:59;1003
  10. Grigg J. Inhaled carbon and lung function in children New England Journal of Medicine 2005;355:1497.
  11. Grigg J. Occupation and Epidemiology Best paper award for 2007; European Respiratory Review 2008;17: 18-19.
  12. Grigg J. The wheezing infant. General Practice Update in press
  13. Grigg J. Environmental particulate pollutants and pulmonary infections in young children In; Allergens, Pollutants and Innate Immunity.Ed; Williams M, in press
  14. Lambert PC, Grigg J. Oral Prednisolone for Children with wheezing New England Journal of Medicine 2009;360;1675

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