Centre for Primary Care and Public Health
Clinical effectiveness group
Pragmatic clinical trials unit
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  - ASAP
  - BELLA
  - Body psychotherapy
  - Calcitriol
  - COPERS
  - DIALECT
  - EMPIRE
  - EPOS
  - FIAT
  - HiLo
  - IRIS
  - LEZ
  - MEDEA
  - Music therapy
  - NESS
  - OEDIPUS
  - OPERA
  - OViD
  - PREP
  - RHIVA 2
  - SNS vs PTNS Pilot
  - TOPAS
  - WAIT
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Current Projects

The PCTU is currently involved in these projects, which are at varying stages of completion and led by a variety of investigators. For further information please click on the title.

Trials
Programmes
Other studies

Trials

BELLA - Development, pilot and feasibility study for a chronic obstructive pulmonary disease (COPD) specific version of the Expert Patients Programme (EPP)

Body Psychotherapy - Effectiveness and processes of body psychotherapy in Chronic schizophrenia

Calcitriol trial - Does 1,25-dihydroxyvitamin D3 (calcitriol) enhance corticosteroid activity in steroid-refractory asthma?

CONFIDeNT - UK multicentre pragmatic randomised double blind placebo-controlled trial of percutaeous tibial nerve stimulation

DIALECT - Dialectical-behaviour therapy for people with borderline personality disorders and self harm - a pragmatic pilot trial

EMPIRE - Antiepileptic drug (AED) management in Pregnancy: An evaluation of effectiveness, cost effectiveness and acceptability of dose adjustment strategies

EPOS - Effective patient-clinician interaction to improve treatment outcomes for patients with psychosis

FIAT - Financial incentives to improve adherence to anti-psychotic maintenance medication in non-adherent patients – a cluster randomised controlled trial

IRIS - Primary care Identification and Referral to Improve Safety of women experiencing partner violence: a randomised controlled trial

MAeSTRO - A feasibility study of a self-management stroke programme (SMP) : a cluster randomised controlled trial

MEDEA - Does the chronic disease self-management programme (expert patient programme) improve metabolic control of diabetes? A randomised controlled trial

Music Therapy - Group music therapy for patients with treatment resistant posttraumatic stress disorder – a pilot randomised controlled trial

NESS - Effectiveness and Cost-Effectiveness of Body Psychotherapy in the Treatment of Negative Symptoms of Schizophrenia – A multi-centre randomised controlled trial

OEDIPUS - Can education for South Asians with asthma and their clinicians reduce unscheduled care? A cluster randomised trial and qualitative evaluation

OPERA - Older people's exercise intervention in residential nursing accommodation

PREP - Development and validation of a Prediction model for Risk of complications in Early onset Pre-eclampsia

RHIVA 2 - Effectiveness of HIV screening in primary care: a cluster RCT and economic analysis

SNS vs PTNS - A randomised mixed methods pilot (phase II exploratory trial) of sacral and percutaneous tibial nerve stimulation for faecal incontinence

WAIT - Parent-determined oral montelukast therapy for preschool wheeze with stratification for arachidonate-5-lipoxygenase (ALOX5) promoter genotype

Programmes

COPERS - COping with Persistent Pain, Effectiveness Research into Self-management

OViD - Effectiveness of vitamin D supplementation to prevent acute respiratory illness and reduce health care use

Other studies

ASAP - Is poor educational attainment in white and Bangladeshi children related to asthma? A study linking health, education and social care datasets

HiLo - High blood pressure control and lipid Lowering in patients at high cardiovascular risk: a cluster-randomised factorial comparison of educational and protocol

LEZ - Impact of the London Low Emission Zone on Children’s Respiratory Health

TOPAS - Measuring and understanding the meaning of chronic widespread pain amongst Bangladeshis in Tower Hamlets, East London